2025
Autoantibody origins in lupus and in relapse post CAR-T therapy
Grenov A, Yoon J, Snell DM, Mikolajczak A, Wang H, Gürel E, Rodriguez Ronchel A, Yegen G, Lee L, Artim Esen B, Rahman A, Maciocia P, Vinuesa CG
bioRxiv 2025 [Preprint]
Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia
Maciocia N, Hoekx M, Acuna C, Wade B, Burley A, Ramanayake S, Nannini F, Wawrzyniecka PA, Karpanasamy T, Schuldt M, Ng S, Ferrari M, Marafioti T, Gritti G, Onuoha S, O'Connor D, Lee L, Mansour M, Khwaja A, Pule M, Maciocia P
Science Translational Medicine 2025; 17(794)
Reply to: Oligoclonality of TRBC1 and TRBC2 in T cell lymphomas
Ferrari M, Parekh F, Maciocia P, Horna P, Thomas S, Sewell AK, Pule M
Nature Communications 2025; 16(1)
CAR T-cell therapies for T-cell malignancies: does cellular immunotherapy represent the best chance of cure?
Maciocia N, Wade B, Maciocia P
Blood Advances 2025; 9(4):913-925
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial
Cwynarski K, Iacoboni G, Tholouli E, Menne T, Irvine DA, Balasubramaniam N, Wood L, Shang J, Xue E, Zhang Y, Basilico S, Neves M, Raymond M, Scott I, El-Kholy M, Jha R, Dainton-Smith H, Hussain R, Day W, Ferrari M, Thomas S, Lilova K, Brugger W, Marafioti T, Lao-Sirieix P, Maciocia P, Pule M
Nature Medicine 2025; 31(1):76-86
In situ tracking of TCR-beta isoforms for detection of T cell clonality
Manipadam MT, Marra A, Ramsay A, Padmasri S, Gosh A, Neves M, Bailey C, Pomplun S, Maciocia P, Cwynarski K, Ferrari M, Lao-Siriex P, Piris M, Falini B, Linch D, Rosenwald A, Pule M, Zamo A, Marafioti T
Hematological Oncology 2025; 43(1):e70018
CD19 chimeric antigen receptor T-cell efficacy and toxicity in adults with Richter's transformation
Hwang A, Kirkwood AA, O'Reilly M, Neill L, Besley C, Paneesha S, Amrith M, Maciocia P, Kuhnl A, Irvine D, Norman J, Abdulgawad A, Gonzalez Arias C, Iyengar S, Marr H, Gohil S, Roddie C
British Journal of Haematology 2025; 207(2):648-653
2024
Single-centre experience of physiotherapist-led prehabilitation for chimeric antigen receptor T cell therapy
McCourt O, Maciocia P, Roddie C, Hwang A, Wood L, Panopoulou A, Springell DA, Al Bakir M, O'Reilly M
eJHaem 2024; 5(5):1062-1066
Dual T-cell constant beta chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry
Horna P, Weybright MJ, Ferrari M, Jungherz D, Peng Y, Akbar Z, Tudor Ilca F, Otteson GE, Seheult JN, Ortmann J, Shi M, Maciocia PM, Herling M, Pule MA, Olteanu H
Blood Cancer Journal 2024; 14(1):34
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies
Ferrari M, Righi M, Baldan V, Wawrzyniecka P, Bulek A, Kinna A, Ma B, Bughda R, Akbar Z, Srivastava S, Gannon I, Robson M, Sillibourne J, Jha R, El-Kholy M, Amin OM, Kokalaki E, Banani MA, Hussain R, Day W, Lim WC, Ghongane P, Hopkins JR, Jungherz D, Herling M, Welin M, Surade S, Dyson M, McCafferty J, Logan D, Cordoba S, Thomas S, Sewell A, Maciocia P, Onuoha S, Pule M
Nature Communications 2024; 15:1-19
2022
A Novel Protein-Based Approach to Generate Allogeneic CAR-T Cells with Simultaneous TCR and MHC Class 1 Downregulation
Karpanasamy T, Wawrzyniecka P, Devereaux S, Kassimatis L, Maciocia NC, Pule M, Maciocia PM
Blood 2022; 140(Supplement 1):636–637 [ASH Abstract]
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia
Maciocia PM, Wawrzyniecka PA, Maciocia NC, Burley A, Karpanasamy T, Devereaux S, Hoekx M, O'Connor D, Leon T, Rapoz-D'Silva T, Pocock R, Rahman S, Gritti G, Yanez DC, Ross S, Crompton T, Williams O, Lee L, Pule MA, Mansour MR
Blood 2022; 140(1):25-37
Chimeric antigen receptor T cells for gamma-delta T cell malignancies
Wawrzyniecka PA, Ibrahim L, Gritti G, Pule MA, Maciocia PM
Leukemia 2022; 36(2):577-579
2017
Targeting the T cell receptor beta-chain constant region for immunotherapy of T cell malignancies
Maciocia PM, Wawrzyniecka PA, Philip B, Ricciardelli I, Akarca AU, Onuoha SC, Legut M, Cole DK, Sewell AK, Gritti G, Somja J, Piris MA, Peggs KS, Linch DC, Marafioti T, Pule MA
Nature Medicine 2017; 23(12):1416-1423
Real-world use of pomalidomide and dexamethasone in double refractory multiple myeloma
Maciocia N, Melville A, Cheesman S, Sharpley F, Ramasamy K, Streetly M, Jenner M, Benjamin R, Schey S, Maciocia P, Popat R, D'sa S, Rismani A, Cerner A, Yong K, Rabin N
British Journal of Haematology 2017; 176(6):908-917