Our Unique Approach

The Maciocia Lab has established an innovative Patient and Public Involvement (PPI) programme that is unusual in its focus on preclinical laboratory research. While most PPI activities in cancer research focus on clinical trials, our group involves patients and members of the public in the earliest stages of our research, from target selection through to experimental design.

Our PPI group was established through a PPI Innovation pilot grant and includes 5-10 members who bring a range of backgrounds and experiences to the table. We meet regularly to discuss the lab's research and ensure patient perspectives shape the direction of our work.

What We Do

Our PPI group meets quarterly to:

  • Review and discuss our ongoing preclinical research programmes
  • Help set research priorities and identify the questions that matter most to patients
  • Provide feedback on study design, outcome measures, and how we communicate our science
  • Ensure our work addresses the real concerns of patients, families, and the public
  • Co-develop materials that make our research accessible to non-specialist audiences

Our Principles

Partnership

Patients are equal partners in shaping our research direction, not passive recipients of information.

Listening

We amplify patient voices and lived experiences to ensure our research is grounded in clinical reality.

Transparency

We share our research openly and honestly, including uncertainties, so our PPI partners can provide meaningful input.

Impact

Our PPI partners have directly influenced our research programme. When they told us that making our research more accessible and bridging the gap between researchers and the public should be a key priority, we listened.

Our PPI group has also contributed to grant applications, reviewed patient-facing materials, and helped us communicate the importance and potential impact of our preclinical discoveries.

Invited Talks & Conferences

Public Lectures

  • UCL World Cancer Day 2026 -Nicola Maciocia, panellist: “Cancer vs. The Computer: How data science, AI and predictive modelling are reshaping cancer care” (February 2026)
  • UCL World Cancer Day 2025 -Paul Maciocia, panellist: “Transforming Cancer Care: UCL Research Innovations and Discoveries” (February 2025)
  • Pint of Science 2022 -Paul Maciocia: “Genetically engineered immune cells to treat cancer”, The Bedford, London (May 2022)
  • Science Museum, London -interactive sessions on CAR-T cell therapy for adults and children
  • Annual UCL/UCLH Open Day -regular participation and lab demonstrations

Media & Educational Resources

  • TED-Ed: “How to biohack your cells to fight cancer” -animated video explaining CAR-T cell therapy, produced in collaboration with UCL colleagues including Martin Pule, designed for GCSE students and the general public
  • UCL Kinesis Podcast -Paul Maciocia: “CAR T-cells: Insights into a pioneering therapy for cancer” (World Cancer Day 2024)
  • BBC Two: War in the Blood -award-winning documentary following CAR-T cell patients at UCLH, featuring our UCL colleagues Claire Roddie and Martin Pule (2019)

If you would like us to speak at your event or school, or if you are interested in visiting the lab, please get in touch.

Get Involved

If you are a patient, carer, or member of the public interested in contributing to cancer immunotherapy research, we would love to hear from you.

Contact Us